BDBM71047 US9546164, 194::US9694002, 194

SMILES Fc1cc(OCC2CCN(CCC(F)(F)F)CC2)c(cc1C(=O)NS(=O)(=O)N1CCC1)C1CC1

InChI Key InChIKey=OKEDOCSVMLVECY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 71047   

TargetSodium channel protein type 5 subunit alpha(Human)
Genentech

US Patent
LigandPNGBDBM71047(US9694002, 194 | US9546164, 194)
Affinity DataIC50: 180nMpH: 7.4 T: 2°CAssay Description:Radioligand Binding Studies: Saturation experiments. A representative compound of formula (I) having a methyl group was tritiated. Three tritiums wer...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2018
Entry Details
US Patent

LigandPNGBDBM71047(US9694002, 194 | US9546164, 194)
Affinity DataIC50: 180nMpH: 7.4 T: 2°CAssay Description:Binding of this radioligand was preformed in 5 mL borosilicate glass test tubes at room temperature. Binding was initiated by adding membranes to inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2018
Entry Details
US Patent