BDBM7405 (2 Z,3 E)-6-Bromo-1-methylindirubin-3 -oxime::6-bromo-3-[(2Z,3E)-3-(hydroxyimino)-2,3-dihydro-1H-indol-2-ylidene]-1-methyl-2,3-dihydro-1H-indol-2-one::6-bromo-N-methyl-indirubin-3 -oxime::indirubin deriv. 13c

SMILES CN1C(=O)C(c2ccc(Br)cc12)c1[nH]c2ccccc2c1N=O

InChI Key InChIKey=LLBYZFGYKBAKSL-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 7405   

TargetCyclin-dependent kinase 1/G2/mitotic-specific cyclin-B(Spiny starfish)
University of Athens

LigandPNGBDBM7405((2 Z,3 E)-6-Bromo-1-methylindirubin-3 -oxime | 6-b...)
Affinity DataIC50: 9.20E+4nMpH: 7.2 T: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2006
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5 activator 1 [99-307](Human)
University of Athens

LigandPNGBDBM7405((2 Z,3 E)-6-Bromo-1-methylindirubin-3 -oxime | 6-b...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2006
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Porcine)
University of Athens

LigandPNGBDBM7405((2 Z,3 E)-6-Bromo-1-methylindirubin-3 -oxime | 6-b...)
Affinity DataIC50: 1.00E+5nMT: 2°CAssay Description:Kinase activities were assayed in buffers containing substrate, enzyme, and inhibitor at 30 °C in the presence of 15 uM ATP/ [gamma-32P] ATP. 32...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/29/2006
Entry Details Article
PubMed