BDBM86637 JNK-IN-12

SMILES CN(C)C\C=C\C(=O)Nc1cccc(c1)C(=O)Nc1ccc(Nc2nccc(n2)C(C#N)c2nc3ccccc3s2)cc1

InChI Key InChIKey=XLLHFYYRDKVYSQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 86637   

TargetMitogen-activated protein kinase 10(Human)
Harvard Medical School

LigandPNGBDBM86637(JNK-IN-12)
Affinity DataIC50: 11nMAssay Description:The binding results were confirmed by measuring IC50 for the inhibition of JNK kinase activity by using Z'-LYTE assay format.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Harvard Medical School

LigandPNGBDBM86637(JNK-IN-12)
Affinity DataIC50: 11.3nMAssay Description:The binding results were confirmed by measuring IC50 for the inhibition of JNK kinase activity by using Z'-LYTE assay format.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2012
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Harvard Medical School

LigandPNGBDBM86637(JNK-IN-12)
Affinity DataIC50: 13nMAssay Description:The binding results were confirmed by measuring IC50 for the inhibition of JNK kinase activity by using Z'-LYTE assay format.More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2012
Entry Details Article
PubMed