BDBM8824 3-(4-{4-amino-6-ethylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3-methylphenyl)urea::CHEMBL366241::N-[4-(4-Amino-6-ethylthieno[2,3-d]pyrimidin-5-yl)-phenyl]-N -(3-methylphenyl)urea::Thienopyrimidine deriv. 74

SMILES CCc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cccc(C)c2)cc1

InChI Key InChIKey=NJPIJBWGCOBYBH-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 8824   

TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM8824(N-[4-(4-Amino-6-ethylthieno[2,3-d]pyrimidin-5-yl)-...)
Affinity DataIC50: 26nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/10/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM8824(N-[4-(4-Amino-6-ethylthieno[2,3-d]pyrimidin-5-yl)-...)
Affinity DataIC50: 26nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Shanghai Jiao Tong University

Curated by ChEMBL
LigandPNGBDBM8824(N-[4-(4-Amino-6-ethylthieno[2,3-d]pyrimidin-5-yl)-...)
Affinity DataIC50: 26.3nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8824(N-[4-(4-Amino-6-ethylthieno[2,3-d]pyrimidin-5-yl)-...)
Affinity DataIC50: 28nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Abbott Laboratories

LigandPNGBDBM8824(N-[4-(4-Amino-6-ethylthieno[2,3-d]pyrimidin-5-yl)-...)
Affinity DataIC50: 28.2nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Dalian University

Curated by ChEMBL
LigandPNGBDBM8824(N-[4-(4-Amino-6-ethylthieno[2,3-d]pyrimidin-5-yl)-...)
Affinity DataIC50: 339nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Dalian University

Curated by ChEMBL
LigandPNGBDBM8824(N-[4-(4-Amino-6-ethylthieno[2,3-d]pyrimidin-5-yl)-...)
Affinity DataIC50: 340nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed