BDBM8848 3-[4-amino-5-(4-{[(3-methylphenyl)carbamoyl]amino}phenyl)thieno[2,3-d]pyrimidin-6-yl]-N-methylpropanamide::3-{4-Amino-5-[4-({[(3-methylphenyl)amino]carbonyl}-amino)phenyl]thieno[2,3-d]pyrimidin-6-yl}-N-methyl-propanamide::Thienopyrimidine deriv. 52

SMILES CNC(=O)CCc1sc2ncnc(N)c2c1-c1ccc(NC(=O)Nc2cccc(C)c2)cc1

InChI Key InChIKey=QNZSSHZYZBZUPX-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 8848   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8848(3-{4-Amino-5-[4-({[(3-methylphenyl)amino]carbonyl}...)
Affinity DataIC50: 330nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8848(3-{4-Amino-5-[4-({[(3-methylphenyl)amino]carbonyl}...)
Affinity DataIC50: 331nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Dalian University

Curated by ChEMBL
LigandPNGBDBM8848(3-{4-Amino-5-[4-({[(3-methylphenyl)amino]carbonyl}...)
Affinity DataIC50: 398nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Dalian University

Curated by ChEMBL
LigandPNGBDBM8848(3-{4-Amino-5-[4-({[(3-methylphenyl)amino]carbonyl}...)
Affinity DataIC50: 400nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Dalian University

Curated by ChEMBL
LigandPNGBDBM8848(3-{4-Amino-5-[4-({[(3-methylphenyl)amino]carbonyl}...)
Affinity DataIC50: 400nMAssay Description:Inhibition of c-Kit by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/17/2010
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Dalian University

Curated by ChEMBL
LigandPNGBDBM8848(3-{4-Amino-5-[4-({[(3-methylphenyl)amino]carbonyl}...)
Affinity DataIC50: 468nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Dalian University

Curated by ChEMBL
LigandPNGBDBM8848(3-{4-Amino-5-[4-({[(3-methylphenyl)amino]carbonyl}...)
Affinity DataIC50: 470nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed