BDBM8855 3-(4-{4-amino-6-benzylthieno[2,3-d]pyrimidin-5-yl}phenyl)-1-(3-methylphenyl)urea::N-[4-(4-Amino-6-benzylthieno[2,3-d]pyrimidin-5-yl)-phenyl]-N -(3-methylphenyl)urea::Thienopyrimidine deriv. 81

SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2c(Cc3ccccc3)sc3ncnc(N)c23)c1

InChI Key InChIKey=UKVIWMOPJDEZMM-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 8855   

TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8855(3-(4-{4-amino-6-benzylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50: 280nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8855(3-(4-{4-amino-6-benzylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50: 282nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Dalian University

Curated by ChEMBL
LigandPNGBDBM8855(3-(4-{4-amino-6-benzylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50: 871nMAssay Description:Inhibition of Tie2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetAngiopoietin-1 receptor(Human)
Dalian University

Curated by ChEMBL
LigandPNGBDBM8855(3-(4-{4-amino-6-benzylthieno[2,3-d]pyrimidin-5-yl}...)
Affinity DataIC50: 880nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed