BDBM8863 3-(4-{4-aminothieno[2,3-d]pyrimidin-5-yl}-3-chlorophenyl)-1-(3-methylphenyl)urea::N-[4-(4-Aminothieno[2,3-d]pyrimidin-5-yl)-3-chloro-phenyl]-N -(3-methylphenyl)urea::Thienopyrimidine deriv. 89

SMILES Cc1cccc(NC(=O)Nc2ccc(-c3csc4ncnc(N)c34)c(Cl)c2)c1

InChI Key InChIKey=RARJZQNSSRFGEU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 8863   

TargetAromatase(Human)
Abbott Laboratories

LigandPNGBDBM8863(N-[4-(4-Aminothieno[2,3-d]pyrimidin-5-yl)-3-chloro...)
Affinity DataIC50: 59nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8863(N-[4-(4-Aminothieno[2,3-d]pyrimidin-5-yl)-3-chloro...)
Affinity DataIC50: 100nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Abbott Laboratories

LigandPNGBDBM8863(N-[4-(4-Aminothieno[2,3-d]pyrimidin-5-yl)-3-chloro...)
Affinity DataIC50: 100nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Dalian University

Curated by ChEMBL
LigandPNGBDBM8863(N-[4-(4-Aminothieno[2,3-d]pyrimidin-5-yl)-3-chloro...)
Affinity DataIC50: 200nMAssay Description:Inhibition of cKITMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Dalian University

Curated by ChEMBL
LigandPNGBDBM8863(N-[4-(4-Aminothieno[2,3-d]pyrimidin-5-yl)-3-chloro...)
Affinity DataIC50: 200nMAssay Description:The assay uses purified enzyme interacting with biotinylated peptide substrate. HTRF is based on the proximity of europium cryptate (donor fluorophor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2006
Entry Details Article
PubMed