BDBM90852 2,3-diphenyl-6-quinoxalinecarboxamide::2,3-diphenylquinoxaline-6-carboxamide::MLS001216320::SMR000544361::US11718589, Compound 5b::cid_4582762

SMILES NC(=O)c1ccc2nc(-c3ccccc3)c(nc2c1)-c1ccccc1

InChI Key InChIKey=HAQCLCJZJWNRQT-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 90852   

Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM90852(MLS001216320 | 2,3-diphenyl-6-quinoxalinecarboxami...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of 15-PGDH (unknown origin) using NAD as substrate measured for 3.5 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
Target15-hydroxyprostaglandin dehydrogenase [NAD(+)](Human)
Ut Southwestern Medical Center

Curated by ChEMBL
LigandPNGBDBM90852(MLS001216320 | 2,3-diphenyl-6-quinoxalinecarboxami...)
Affinity DataIC50: 2.50E+3nMAssay Description:This Example provides data on two groups (Table 1 and Table 2) of structural analogues of identified 15-PGDH inhibitors. Data provided is the IC50 of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2023
Entry Details
US Patent

TargetCorticotropin-releasing factor-binding protein(Human)
Burnham Center For Chemical Genomics

Curated by PubChem BioAssay
LigandPNGBDBM90852(MLS001216320 | 2,3-diphenyl-6-quinoxalinecarboxami...)
Affinity DataEC50: >5.30E+4nMAssay Description:Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2012
Entry Details
PCBioAssay