BDBM97230 2-[[(E)-3-(4-methoxyphenyl)-1-oxoprop-2-enyl]amino]benzoic acid::2-[[(E)-3-(4-methoxyphenyl)acryloyl]amino]benzoic acid::2-[[(E)-3-(4-methoxyphenyl)prop-2-enoyl]amino]benzoic acid::MLS000774680::SMR000372439::cid_2400427

SMILES COc1ccc(\C=C\C(=O)Nc2ccccc2C(O)=O)cc1

InChI Key InChIKey=CKQMTXLABQTGQB-UHFFFAOYSA-N

Data  4 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 97230   

LigandPNGBDBM97230(2-[[(E)-3-(4-methoxyphenyl)prop-2-enoyl]amino]benz...)
Affinity DataIC50: 1.20E+4nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of CA-induced increase in calcium influx incubated for 10 mins pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandPNGBDBM97230(2-[[(E)-3-(4-methoxyphenyl)prop-2-enoyl]amino]benz...)
Affinity DataIC50: 1.26E+4nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of CA-induced increase in calcium influx incubated for 10 mins pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandPNGBDBM97230(2-[[(E)-3-(4-methoxyphenyl)prop-2-enoyl]amino]benz...)
Affinity DataEC50:  4.90E+4nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
LigandPNGBDBM97230(2-[[(E)-3-(4-methoxyphenyl)prop-2-enoyl]amino]benz...)
Affinity DataEC50:  5.01E+4nMAssay Description:Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetSteroidogenic factor 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM97230(2-[[(E)-3-(4-methoxyphenyl)prop-2-enoyl]amino]benz...)
Affinity DataIC50: 6.75E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay
TargetNuclear receptor subfamily 0 group B member 1(Human)
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM97230(2-[[(E)-3-(4-methoxyphenyl)prop-2-enoyl]amino]benz...)
Affinity DataIC50: 6.75E+4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2013
Entry Details
PCBioAssay