BDBM26061 5-(benzylsulfanyl)-1-phenyl-1H-1,2,3,4-tetrazole::BI-83B3

SMILES C(Sc1nnnn1-c1ccccc1)c1ccccc1

InChI Key InChIKey=YGJVZCBHFFYTPP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26061   

TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM26061(5-(benzylsulfanyl)-1-phenyl-1H-1,2,3,4-tetrazole |...)
Affinity DataIC50: 2.50E+4nMpH: 7.8 T: 2°CAssay Description:Compound was evaluated for its ability to disrupt the interaction of pepJIP1 with JNK1 by using DELFIA assay. DELFIA is a heterogeneous assay whereby...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Burnham Institute For Medical Research

LigandPNGBDBM26061(5-(benzylsulfanyl)-1-phenyl-1H-1,2,3,4-tetrazole |...)
Affinity DataIC50: 1.00E+5nMpH: 7.5 T: 2°CAssay Description:Compounds were tested for their ability to inhibit JNK1 phosphorylation of ATF2 in the Time-Resolved Fluorescence Resonance Energy Transfer (TR-FRET)...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2008
Entry Details Article
PubMed