BDBM50225698 CHEBI:34791::Cyclaine::Hexylcaine

SMILES CC(CNC1CCCCC1)OC(=O)c1ccccc1

InChI Key InChIKey=DKLKMKYDWHYZTD-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50225698   

TargetSodium channel protein type 1/2/3 subunit alpha(Human)
TBA

Curated by ChEMBL

LigandBDBM50225698(CHEBI:34791 | Cyclaine | Hexylcaine)Copy SMILESCopy InChI

Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of binding of Batrachotoxinin [3H]BTX-B to high affinity sites on voltage dependent sodium channels in a vesicular preparation from guinea...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
12/14/2018
Entry Details Article
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TargetBile salt export pump(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50225698(CHEBI:34791 | Cyclaine | Hexylcaine)Copy SMILESCopy InChI

Affinity DataIC50: 5.06E+5nMAssay Description:Inhibition of human BSEP expressed in baculovirus transfected fall armyworm Sf21 cell membranes vesicles assessed as reduction in ATP-dependent [3H]-...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseKEGGPC cidPC sidSimilars

In Depth
Date in BDB:
9/28/2019
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL