BDBM1894 1-(2-phenylethyl)-3-1,3-thiazol-2-ylthiourea::CHEMBL33981::LY73497::N-(2-phenethyl)-N -(2-thiazolyl)thiourea::Phenylethylthiazolylthiourea (PETT) Analog

SMILES S=C(NCCc1ccccc1)Nc1nccs1

InChI Key InChIKey=ANUSGJXVCFPWMQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 1894   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Eli Lilly

LigandPNGBDBM1894(CHEMBL33981 | Phenylethylthiazolylthiourea (PETT) ...)
Affinity DataIC50: 900nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/25/2004
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Sree Chaitanya College

Curated by ChEMBL
LigandPNGBDBM1894(CHEMBL33981 | Phenylethylthiazolylthiourea (PETT) ...)
Affinity DataIC50: 900nMAssay Description:Inhibition of HIV-1 reverse transcriptase using and rCdC as template and tritium-labeled dGTP incubated for 30 mins by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/1/2017
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Medivir

Curated by ChEMBL
LigandPNGBDBM1894(CHEMBL33981 | Phenylethylthiazolylthiourea (PETT) ...)
Affinity DataIC50: 900nMAssay Description:Antiviral activity was determined against HIV- 1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed