BDBM50265443 6-chloro-2-methoxy-N-(pyridin-3-yl)acridin-9-amine::CHEMBL495567::NSC-12999

SMILES COc1ccc2nc3cc(Cl)ccc3c(Nc3cccnc3)c2c1

InChI Key InChIKey=LUUDYHCKONVRQY-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50265443   

TargetAromatase(Human)
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50265443(6-chloro-2-methoxy-N-(pyridin-3-yl)acridin-9-amine...)
Affinity DataKi:  25.5nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by Lineweaver-Burke plot in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetAromatase(Human)
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50265443(6-chloro-2-methoxy-N-(pyridin-3-yl)acridin-9-amine...)
Affinity DataIC50: 76nMAssay Description:Inhibition of human aromatase-mediated conversion of [1beta3H]androstenedione to estrone by liquid scintillation counting in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed