BDBM50219053 CHEMBL242004::N-(3-{1-4-(3,4-difluorophenoxy)benzyl]-4-piperidinyl}-4-methylphenyl)-2-methylpropanamide::SNAP-94847

SMILES Cc1ccc(cc1C2CCN(CC2)Cc3ccc(cc3)Oc4ccc(c(c4)F)F)NC(=O)C(C)C

InChI Key InChIKey=VMLZFUVIKCGATC-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50219053   

TargetMelanin-concentrating hormone receptor 1(Rat)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50219053(N-(3-{1-4-(3,4-difluorophenoxy)benzyl]-4-piperidin...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H]T-226296 from rat recombinant MCH1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50219053(N-(3-{1-4-(3,4-difluorophenoxy)benzyl]-4-piperidin...)
Affinity DataKi:  180nMAssay Description:Displacement of [125I]HEAT from human recombinant adrenergic alpha-1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetMelanin-concentrating hormone receptor 1(Rat)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50219053(N-(3-{1-4-(3,4-difluorophenoxy)benzyl]-4-piperidin...)
Affinity DataIC50: 230nMAssay Description:Antagonist activity at rat MCH1 receptor expressed in HEK293 cells by FLIPR calcium mobility assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50219053(N-(3-{1-4-(3,4-difluorophenoxy)benzyl]-4-piperidin...)
Affinity DataKi:  7.40E+3nMAssay Description:Displacement of [3H]spiperone from human recombinant dopamine D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed