BDBM10 CHEMBL12193::delta-valerolactam::piperidin-2-one

SMILES: C1CCNC(=O)C1

InChI Key: InChIKey=XUWHAWMETYGRKB-UHFFFAOYSA-N

Data: 2 KI  1 Kd  2 ITC

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 10   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peptidyl-prolyl cis-trans isomerase FKBP5 (Human)	BDBM10 (CHEMBL12193 | piperidin-2-one | delta-valerolactam) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	2.80E+6	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Protein cereblon (Human)	BDBM10 (CHEMBL12193 | piperidin-2-one | delta-valerolactam) Show SMILES Show InChI	GoogleScholar	UniChem		1.46E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alcohol dehydrogenase E/S chain (Horse)	BDBM10 (CHEMBL12193 | piperidin-2-one | delta-valerolactam) Show SMILES Show InChI	GoogleScholar	UniChem		1.30E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair

Activity Spreadsheet -- ITC Data from BindingDB

Found 2 hits for monomerid = 10

Cell (A)	Syringe (B)	Cell Links	Syringe Links	Cell + Syr Links	ΔG° kcal/mole	-TΔS° kcal/mole	ΔH° kcal/mole	log K	pH	Temp °C
BDBM4	BDBM10				-0.955	1.92	-2.87	0.699	6.90	25
TBA					Details of this binding reaction
BDBM11	BDBM10				-1.91	-0.997	-0.884	1.40	6.90	25
TBA					Details of this binding reaction