BDBM10020 (2-bromo-4-{[(4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino]methyl}phenyl) sulfamate::JMC503540 Compound 5::YM511 Analog 5::YM511-based dual aromatase-sulfatase inhibitor (DASI) 7::dual aromatase-sulfatase inhibitor 7
SMILES NS(=O)(=O)Oc1ccc(CN(c2ccc(cc2)C#N)n2cnnc2)cc1Br
InChI Key InChIKey=GHDKYBCUDPSXGJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 9 hits for monomerid = 10020
Affinity DataIC50: 0.820nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
Affinity DataIC50: 137nMpH: 7.8 T: 2°CAssay Description:The in vitro inhibition of carbonic anhydrase was assessed by a colorimetric assay. Carbonic anhydrase-catalysed hydrolysis of p-nitrophenyl acetate ...More data for this Ligand-Target Pair
Affinity DataIC50: 0.820nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of sulfatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 0.820nMAssay Description:Inhibition of aromatase in human JEG-3 cells using [1beta-3H]androstenedione after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:Inhibition of steroid sulfatase in human JEG-3 cells using [6,7-3H]E1S after 1 hr by scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataIC50: 0.820nMAssay Description:Inhibition of aromatase (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 39nMAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair