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BDBM100307 US8501749, 7

SMILES: Cc1cccc2n(C)cc(Cn3c4ccncc4c(=O)n(CC(O)=O)c3=O)c12

InChI Key: InChIKey=SFGGOOQUWZLSAF-UHFFFAOYSA-N

Data: 1 IC50

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100307   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chymase


(Homo sapiens (human))
BDBM100307
PNG
(US8501749, 7)
Show SMILES Cc1cccc2n(C)cc(Cn3c4ccncc4c(=O)n(CC(O)=O)c3=O)c12
Show InChI InChI=1S/C20H18N4O4/c1-12-4-3-5-16-18(12)13(9-22(16)2)10-23-15-6-7-21-8-14(15)19(27)24(20(23)28)11-17(25)26/h3-9H,10-11H2,1-2H3,(H,25,26)
PDB
MMDB

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PC sid
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Similars

US Patent
n/an/a 9.60n/an/an/an/a8.028



Boehringer Ingelheim International GmbH

US Patent


Assay Description
In vitro inhibition assay of Chymase.


US Patent US8501749 (2013)


BindingDB Entry DOI: 10.7270/Q28G8JB2
More data for this
Ligand-Target Pair