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BDBM100337 US8501749, 37

SMILES: CC[C@@H](C(O)=O)n1c(=O)n(Cc2nsc3cc(C)cc(C)c23)c2cccnc2c1=O

InChI Key: InChIKey=KUZGYFDAONROEN-AWEZNQCLSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 100337   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Chymase


(Homo sapiens (human))
BDBM100337
PNG
(US8501749, 37)
Show SMILES CC[C@@H](C(O)=O)n1c(=O)n(Cc2nsc3cc(C)cc(C)c23)c2cccnc2c1=O
Show InChI InChI=1S/C21H20N4O4S/c1-4-14(20(27)28)25-19(26)18-15(6-5-7-22-18)24(21(25)29)10-13-17-12(3)8-11(2)9-16(17)30-23-13/h5-9,14H,4,10H2,1-3H3,(H,27,28)/t14-/m0/s1
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MMDB

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PC sid
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Similars

US Patent
n/an/a 2.70n/an/an/an/a8.028



Boehringer Ingelheim International GmbH

US Patent


Assay Description
In vitro inhibition assay of Chymase.


US Patent US8501749 (2013)


BindingDB Entry DOI: 10.7270/Q28G8JB2
More data for this
Ligand-Target Pair