BDBM10048 (2R,15S)-15-methyl-2-[3-(methylsulfanyl)propyl]tetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-1(17),6-diene-5,14-dione::3,17-Dioxo-19-[(methylthio)ethyl]androsta-4,9(11)-diene::RU54115 Analog 54

SMILES CSCCC[C@]12CCC(=O)C=C1CCC1C3CCC(=O)[C@@]3(C)CC=C21

InChI Key InChIKey=NXBZLFOYWHWZLN-OWXVKCJTSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10048   

TargetAromatase(Homo sapiens (Human))
Centre De Recherche De Roussel Uclaf

LigandPNGBDBM10048((2R,15S)-15-methyl-2-[3-(methylsulfanyl)propyl]tet...)
Affinity DataIC50: >1.00E+4nMpH: 7.2 T: 2°CAssay Description:The enzyme activity was assayed by measuring the formation of tritiated water from [1beta, 2beta-3H ]androstenedione in the presence of increasing co...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed