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BDBM101747 US8530490, 7

SMILES: Fc1ccc(CNS(=O)(=O)CCCOCn2ccc(=O)[nH]c2=O)cc1OCC1CC1

InChI Key: InChIKey=YMLSRXUBLKDSRY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 101747   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase)


(Homo sapiens (Human))
BDBM101747
PNG
(US8530490, 7)
Show SMILES Fc1ccc(CNS(=O)(=O)CCCOCn2ccc(=O)[nH]c2=O)cc1OCC1CC1
Show InChI InChI=1S/C19H24FN3O6S/c20-16-5-4-15(10-17(16)29-12-14-2-3-14)11-21-30(26,27)9-1-8-28-13-23-7-6-18(24)22-19(23)25/h4-7,10,14,21H,1-3,8-9,11-13H2,(H,22,24,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 640n/an/an/an/a7.437



Taiho Pharmaceutical Co., Ltd

US Patent


Assay Description
The inhibitory activity of these compounds of the present invention against human dUTPase was determined by measuring the production of [5-3H]deoxyur...


US Patent US8883759 (2014)


BindingDB Entry DOI: 10.7270/Q27943CK
More data for this
Ligand-Target Pair
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase)


(Homo sapiens (Human))
BDBM101747
PNG
(US8530490, 7)
Show SMILES Fc1ccc(CNS(=O)(=O)CCCOCn2ccc(=O)[nH]c2=O)cc1OCC1CC1
Show InChI InChI=1S/C19H24FN3O6S/c20-16-5-4-15(10-17(16)29-12-14-2-3-14)11-21-30(26,27)9-1-8-28-13-23-7-6-18(24)22-19(23)25/h4-7,10,14,21H,1-3,8-9,11-13H2,(H,22,24,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 640n/an/an/an/an/an/a



Taiho Pharmaceutical Co., Ltd

US Patent


Assay Description
The inhibitory activity of the compound against human dUTPase was determined by measuring the production of [5-3H]deoxyuridine monophosphate from [5-...


US Patent US8530490 (2013)


BindingDB Entry DOI: 10.7270/Q25H7DX2
More data for this
Ligand-Target Pair