BindingDB logo
myBDB logout

BDBM101820 US8530490, 80

SMILES: CC(C)C[C@@H](NS(=O)(=O)CCCOCn1ccc(=O)[nH]c1=O)C(O)(c1ccccc1)c1ccccc1

InChI Key: InChIKey=AOWQVTANJSJDTM-QWVACARCNA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 101820   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Deoxyuridine 5'-triphosphate nucleotidohydrolase (dUTPase)


(Homo sapiens (Human))
BDBM101820
PNG
(US8530490, 80)
Show SMILES CC(C)C[C@@H](NS(=O)(=O)CCCOCn1ccc(=O)[nH]c1=O)C(O)(c1ccccc1)c1ccccc1
Show InChI InChI=1/C26H33N3O6S/c1-20(2)18-23(26(32,21-10-5-3-6-11-21)22-12-7-4-8-13-22)28-36(33,34)17-9-16-35-19-29-15-14-24(30)27-25(29)31/h3-8,10-15,20,23,28,32H,9,16-19H2,1-2H3,(H,27,30,31)/t23-/s2
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 1.30E+3n/an/an/an/an/an/a



Taiho Pharmaceutical Co., Ltd.

US Patent


Assay Description
The inhibitory activity of the compound against human dUTPase was determined by measuring the production of [5-3H]deoxyuridine monophosphate from [5-...


US Patent US8530490 (2013)


BindingDB Entry DOI: 10.7270/Q25H7DX2
More data for this
Ligand-Target Pair