BDBM10245 3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6.4.0.0^{2,6}]dodeca-1(12),6,8,10-tetraene::CHEMBL53554::NSC 625487::TBZ::Thiazolobenzimidazole

SMILES: Fc1cccc(F)c1C1SCc2nc3ccccc3n12

InChI Key: InChIKey=AMLBAOPYPUXEQF-UHFFFAOYSA-N

Data: 2 IC50  13 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 10245   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Gag-Pol polyprotein [588-1027]/[588-1147] (Human immunodeficiency virus type 1)	BDBM10245 (3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.46E+4	n/a	n/a	n/a	n/a	7.5	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM10245 (3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM10245 (3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM10245 (3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM10245 (3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM10245 (3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM10245 (3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	700	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM10245 (3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM10245 (3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM10245 (3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM10245 (3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM10245 (3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.45E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM10245 (3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.77E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM10245 (3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Reverse transcriptase/RNaseH (Human immunodeficiency virus type 1)	BDBM10245 (3-(2,6-difluorophenyl)-4-thia-2,7-diazatricyclo[6....) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair