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BDBM10247 1,2,3,4-tetrahydroisoquinoline-1,3,4-trione::Isoquinoline-1,3,4-trione 1::hsp90_153

SMILES: c1ccc2c(c1)C(=O)C(=O)NC2=O

InChI Key: InChIKey=YIOFGHHAURBGSJ-UHFFFAOYSA-N

Data: 6 IC50

PDB links: 1 PDB ID matches this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 10247
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Caspase-3 (Human)	BDBM10247 (1,2,3,4-tetrahydroisoquinoline-1,3,4-trione \| Isoq...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	149	n/a	n/a	n/a	n/a	7.5	35
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Caspase-2 (Human)	BDBM10247 (1,2,3,4-tetrahydroisoquinoline-1,3,4-trione \| Isoq...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Caspase-6 (Human)	BDBM10247 (1,2,3,4-tetrahydroisoquinoline-1,3,4-trione \| Isoq...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	474	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Caspase-7 (Human)	BDBM10247 (1,2,3,4-tetrahydroisoquinoline-1,3,4-trione \| Isoq...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	386	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Caspase-8 (Human)	BDBM10247 (1,2,3,4-tetrahydroisoquinoline-1,3,4-trione \| Isoq...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.91E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair
Heat shock protein HSP 90-beta (Human)	BDBM10247 (1,2,3,4-tetrahydroisoquinoline-1,3,4-trione \| Isoq...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
TBA					More data for this Ligand-Target Pair