BDBM102555 US8536172, I-4

SMILES CS(=O)(=O)N[C@H]1CC[C@H](Nc2nccc(-n3ccc4c(N5CCC(O)CC5)cccc43)n2)CC1

InChI Key InChIKey=UWVMWKPLLYHFSP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 102555   

TargetMitogen-activated protein kinase 8(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 102555BDBM102555(US8536172, I-4)
Affinity DataIC50: 42.9nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2013
Entry Details
US Patent

TargetMitogen-activated protein kinase 8(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 102555BDBM102555(US8536172, I-4)
Affinity DataIC50: 292nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2013
Entry Details
US Patent