BDBM102572 US8536172, I-21

SMILES C[C@@H]1CN(CCN1c1cccc2n(ccc12)-c1ccnc(N[C@H]2CC[C@@H](CC2)C(=O)N2CCC(O)CC2)n1)C(C)=O

InChI Key InChIKey=QWMRHTSYBNPHKO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 102572   

TargetMitogen-activated protein kinase 8(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 102572BDBM102572(US8536172, I-21)
Affinity DataIC50: 31.2nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2013
Entry Details
US Patent

TargetMitogen-activated protein kinase 8(Human)
Roche Palo Alto

US Patent
LigandChemical structure of BindingDB Monomer ID 102572BDBM102572(US8536172, I-21)
Affinity DataIC50: 138nMpH: 7.5Assay Description:JNK activity was measured by phosphorylation of GST-ATF2 (19-96) with [gamma-33P] ATP.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/18/2013
Entry Details
US Patent