BDBM102620 BMX-IN-1::N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[h][1,::US10000483, Compound I-14

SMILES: Cc1ccc(cc1NC(=O)C=C)-n1c2c(ccc1=O)cnc1ccc(cc21)-c1ccc(NS(C)(=O)=O)cc1

InChI Key: InChIKey=SFMJNHNUOVADRW-UHFFFAOYSA-N

Data: 1 KI  20 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 102620   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase BTK (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10.4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase BTK (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Blk (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	377	n/a	n/a	n/a	n/a	n/a	n/a
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Cytoplasmic tyrosine-protein kinase BMX (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Tec (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	653	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase ITK/TSK (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Epidermal growth factor receptor [696-1210,T790M] (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK3 [1-973] (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
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Cytoplasmic tyrosine-protein kinase BMX (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.99	n/a	n/a	n/a	n/a	n/a	n/a
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Cytoplasmic tyrosine-protein kinase BMX (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Blk (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	377	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase JAK3 (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 2 group C member 2 (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Tec (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	653	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase Blk (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	377	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase mTOR (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	325	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cytoplasmic tyrosine-protein kinase BMX (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Human)	BDBM102620 (N-[5-[9-[4-(methanesulfonamido)phenyl]-2-oxobenzo[...) Show SMILES Show InChI	GoogleScholar	UniChem		3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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