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BDBM102932 US8541447, 8

SMILES: O=C(NC1C2CCN(CC2)C1Cc1cccnc1)c1ccc(Sc2ccccc2)cc1

InChI Key: InChIKey=RUHFKYBMZVVZRM-UHFFFAOYNA-N

Data: 1 KI

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 102932   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Neuronal acetylcholine receptor protein alpha-7 subunit


(Homo sapiens (Human))
BDBM102932
PNG
(US8541447, 8)
Show SMILES O=C(NC1C2CCN(CC2)C1Cc1cccnc1)c1ccc(Sc2ccccc2)cc1
Show InChI InChI=1/C26H27N3OS/c30-26(21-8-10-23(11-9-21)31-22-6-2-1-3-7-22)28-25-20-12-15-29(16-13-20)24(25)17-19-5-4-14-27-18-19/h1-11,14,18,20,24-25H,12-13,15-17H2,(H,28,30)
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
9n/an/an/an/an/an/an/an/a



Targacept Inc

US Patent


Assay Description
Binding assay using alpha 7 nAChR.


US Patent US8541447 (2013)


BindingDB Entry DOI: 10.7270/Q2B56HCV
More data for this
Ligand-Target Pair