BDBM10297 1-methyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione::Isatin analog 1

SMILES: CN1C(=O)C(=O)c2cc(ccc12)N(=O)=O

InChI Key: InChIKey=JPTDPTOWOMFBRY-UHFFFAOYSA-N

Data: 8 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 10297   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Caspase-7 (Human)	BDBM10297 (1-methyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione |...) Show SMILES Show InChI	GoogleScholar	UniChem		290	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-3 (Human)	BDBM10297 (1-methyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione |...) Show SMILES Show InChI	GoogleScholar	UniChem		500	-8.73	1.00E+3	n/a	n/a	n/a	n/a	7.5	30
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Caspase-6 (Human)	BDBM10297 (1-methyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione |...) Show SMILES Show InChI	GoogleScholar	UniChem		1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-4 (Human)	BDBM10297 (1-methyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione |...) Show SMILES Show InChI	GoogleScholar	UniChem		4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-9 (Human)	BDBM10297 (1-methyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione |...) Show SMILES Show InChI	GoogleScholar	UniChem		7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-1 (Human)	BDBM10297 (1-methyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione |...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-2 (Human)	BDBM10297 (1-methyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione |...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Caspase-8 (Human)	BDBM10297 (1-methyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione |...) Show SMILES Show InChI	GoogleScholar	UniChem		>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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