Molecular Structure for 10298

Molecular Structure for 10298

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Isatin analog 2 1-benzyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione

Data: 8 KI 1 IC50

Vconf -m prep

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CSLS Chemical Structure Lookup Service
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits in this search
Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
Caspase-4 Homo sapiens (human)	Isatin analog 2 (1-benzyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione)	GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	5000.0	-30.764	n/a	n/a	n/a	5.8	30
GlaxoSmithKline		GoogleScholar KEGG UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	J Med Chem. 44: 2015-26 (2001)
Caspase-7 Homo sapiens (human)	Isatin analog 2 (1-benzyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	170.00	-39.286	n/a	n/a	n/a	7.5	30
GlaxoSmithKline			CSLS PC cid PC sid	PubMed	J Med Chem. 44: 2015-26 (2001)
Caspase-8 Homo sapiens (human)	Isatin analog 2 (1-benzyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	31000	-26.165	n/a	n/a	n/a	7.5	30
GlaxoSmithKline			CSLS PC cid PC sid	PubMed	J Med Chem. 44: 2015-26 (2001)
Caspase-9 Homo sapiens (human)	Isatin analog 2 (1-benzyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	5000.0	-30.764	n/a	n/a	n/a	6.5	30
GlaxoSmithKline			CSLS PC cid PC sid	PubMed	J Med Chem. 44: 2015-26 (2001)
Caspase-2 Homo sapiens (human)	Isatin analog 2 (1-benzyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	>25000	>-26.707	n/a	n/a	n/a	6.2	30
GlaxoSmithKline			CSLS PC cid PC sid	PubMed	J Med Chem. 44: 2015-26 (2001)
Caspase-6 Homo sapiens (human)	Isatin analog 2 (1-benzyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione)	GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	1000.0	-34.820	n/a	n/a	n/a	7.4	30
GlaxoSmithKline		GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt	CSLS PC cid PC sid	PubMed	J Med Chem. 44: 2015-26 (2001)
Caspase-3 Homo sapiens (human)	Isatin analog 2 (1-benzyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	130.00	-39.962	250.0	n/a	n/a	7.5	30
GlaxoSmithKline			CSLS PC cid PC sid	PubMed	J Med Chem. 44: 2015-26 (2001)
Caspase-1 Homo sapiens (human)	Isatin analog 2 (1-benzyl-5-nitro-2,3-dihydro-1H-indole-2,3-dione)	B.MOAD DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CSLS PC cid PC sid	PubMed	18000	-27.535	n/a	n/a	n/a	7.5	30
GlaxoSmithKline			CSLS PC cid PC sid	PubMed	J Med Chem. 44: 2015-26 (2001)