BDBM103387 US8546380, 731::US8633188, 731

SMILES Cc1cc(C(=O)Nc2cc(Br)cc(c2)C2(C)CCSC(N)=N2)c(C)o1

InChI Key InChIKey=MTQUNEVSXBMCID-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103387   

TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM103387(US8546380, 731 | US8633188, 731)
Affinity DataIC50:  278nMpH: 5.0 T: 2°CAssay Description:Zero point five μL of the test compounds (dissolved in N,N′-dimethylsulfoxide) were incubated with 48.5 μL of the fluorescence-quench...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetBeta-secretase 1(Homo sapiens (Human))
Shionogi

US Patent
LigandPNGBDBM103387(US8546380, 731 | US8633188, 731)
Affinity DataIC50:  278nMpH: 5.0 T: 2°CAssay Description:Inhibition assay using beta-Secretase activity.More data for this Ligand-Target Pair
In DepthDetails US Patent