BDBM103499 US8552023, 11

SMILES C[C@@H](N(C\C=C\c1cnc2C[C@]3(Cc2c1)C(=O)Nc1ncccc31)C(=O)C1(CC1)C(F)(F)F)c1cc(F)cc(F)c1

InChI Key InChIKey=IENHCDUZUNPICI-RXPOHSHGSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103499   

TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM103499(US8552023, 11)Copy SMILESCopy InChI

Affinity DataKi:  0.0500nMAssay Description:Displacement of [125I]-hCGRP from human CALCRL/RAMP1 expressed in HEK293 cell membranesMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent

LigandBDBM103499(US8552023, 11)Copy SMILESCopy InChI

Affinity DataKi:  0.0500nMpH: 7.4Assay Description:Inhibition of the binding of 125I-CGRP to receptors and functional antagonism of CGRP receptors were determined using native receptor binding assay.More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI