BDBM103501 US8552023, 13

SMILES C[C@@H](N(C\C=C\c1cnc2C[C@]3(Cc2c1)C(=O)Nc1ncccc31)C(=O)C(C)(C)C)c1ccc(C)c(F)c1

InChI Key InChIKey=CUZDSMAQNGFFFO-QFSLHFMNSA-N

Data  2 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 103501   

TargetCalcitonin gene-related peptide type 1 receptor/Receptor activity-modifying protein 1(Homo sapiens (Human))
Merck

Curated by ChEMBL

LigandBDBM103501(US8552023, 13)Copy SMILESCopy InChI

Affinity DataKi:  0.130nMAssay Description:Displacement of [125I]-hCGRP from human CALCRL/RAMP1 expressed in HEK293 cell membranesMore data for this Ligand-Target Pair

Target InfoPDBReactome pathwayKEGG
UniProtKB/SwissProt
antibodypediaantibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails ArticlePubMed
Copy BDB DOI

TargetCalcitonin gene-related peptide type 1 receptor(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent

LigandBDBM103501(US8552023, 13)Copy SMILESCopy InChI

Affinity DataKi:  0.130nMpH: 7.4Assay Description:Inhibition of the binding of 125I-CGRP to receptors and functional antagonism of CGRP receptors were determined using native receptor binding assay.More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
antibodypediaGoogleScholar

Ligand InfoPC cidPC sidSimilars

In DepthDetails US Patent
Copy BDB DOI