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BDBM103685 US8563553, 110

SMILES: CC(C)(C)c1nc(c([nH]1)-c1cc(F)cc(NS(C)(=O)=O)c1Cl)-c1ccnc(N)n1

InChI Key: InChIKey=VSPVANQWTANQSS-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 103685   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
B-RAF V600E


(Homo sapiens (Human))
BDBM103685
PNG
(US8563553, 110)
Show SMILES CC(C)(C)c1nc(c([nH]1)-c1cc(F)cc(NS(C)(=O)=O)c1Cl)-c1ccnc(N)n1
Show InChI InChI=1S/C18H20ClFN6O2S/c1-18(2,3)16-24-14(15(25-16)11-5-6-22-17(21)23-11)10-7-9(20)8-12(13(10)19)26-29(4,27)28/h5-8,26H,1-4H3,(H,24,25)(H2,21,22,23)
PDB

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 5n/an/an/an/a7.5n/a



Novartis AG

US Patent


Assay Description
Raf/Mek amplified luminescence proximity homogeneous assay.


US Patent US8563553 (2013)


BindingDB Entry DOI: 10.7270/Q2ZP44R7
More data for this
Ligand-Target Pair