BDBM103836 Vaniprevir

SMILES CC[C@@H]1C[C@]1(NC(=O)[C@@H]1C[C@@H]2CN1C(=O)[C@@H](NC(=O)OCC(C)(C)CCCCc1cccc3CN(Cc13)C(=O)O2)C(C)(C)C)C(=O)NS(=O)(=O)C1CC1

InChI Key InChIKey=KUQWGLQLLVFLSM-ONAXAZCASA-N

Data  1 KI

PDB links: 5 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 103836   

TargetGenome polyprotein(Hepatitis C virus (HCV genotype 1a, isolate H))
University Of Massachusetts Medical School

LigandPNGBDBM103836(Vaniprevir)
Affinity DataKi:  0.460nMAssay Description:NS3/4A protease was preincubated with increasing concentration of drugs in protease reaction buffer for 1 hour. Inhibition assays were performed in ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed