BDBM10439 (5S)-5-[(10-{[(5S)-2-oxo-1,2,5,6,7,8-hexahydroquinolin-5-yl]amino}decyl)amino]-1,2,5,6,7,8-hexahydroquinolin-2-one::(S,S)-(-)-bis(10)-hupyridone

SMILES O=c1ccc2[C@H](CCCc2[nH]1)NCCCCCCCCCCN[C@H]1CCCc2[nH]c(=O)ccc12

InChI Key InChIKey=CKFAWHBPSZAYLS-ZEQRLZLVSA-N

Data  2 KI  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 10439   

TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Universit£

Curated by ChEMBL
LigandPNGBDBM10439((5S)-5-[(10-{[(5S)-2-oxo-1,2,5,6,7,8-hexahydroquin...)
Affinity DataKi:  0.800nMAssay Description:Inhibition of Torpedo californica AChEMore data for this Ligand-Target Pair
TargetAcetylcholinesterase(Tetronarce californica (Pacific electric ray) (Tor...)
Universit£

Curated by ChEMBL
LigandPNGBDBM10439((5S)-5-[(10-{[(5S)-2-oxo-1,2,5,6,7,8-hexahydroquin...)
Affinity DataKi:  0.800nM ΔG°:  -12.3kcal/mole IC50:  2.40nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM10439((5S)-5-[(10-{[(5S)-2-oxo-1,2,5,6,7,8-hexahydroquin...)
Affinity DataIC50:  151nMAssay Description:Inhibition of rat AChEMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Rattus norvegicus (rat))
Universit£

Curated by ChEMBL
LigandPNGBDBM10439((5S)-5-[(10-{[(5S)-2-oxo-1,2,5,6,7,8-hexahydroquin...)
Affinity DataIC50:  151nMpH: 7.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed