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BDBM104525 US8575201, 16

SMILES: Nc1ncc(cn1)-c1ccc(cn1)C1(CCC1)c1noc(n1)-c1ccc(NCC(O)=O)nc1

InChI Key: InChIKey=KTCNCLBKQXABAZ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 104525   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM104525
PNG
(US8575201, 16)
Show SMILES Nc1ncc(cn1)-c1ccc(cn1)C1(CCC1)c1noc(n1)-c1ccc(NCC(O)=O)nc1
Show InChI InChI=1S/C22H20N8O3/c23-21-27-9-14(10-28-21)16-4-3-15(11-24-16)22(6-1-7-22)20-29-19(33-30-20)13-2-5-17(25-8-13)26-12-18(31)32/h2-5,8-11H,1,6-7,12H2,(H,25,26)(H,31,32)(H2,23,27,28)
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MMDB

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PC sid
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Similars

US Patent
n/an/a 11n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Compounds area assessed for the ability to bind to FLAP in a binding assay that measures compound-specific displacement of an iodinated (125I) FLAP i...


US Patent US8575201 (2013)


BindingDB Entry DOI: 10.7270/Q2ZK5FBX
More data for this
Ligand-Target Pair