BDBM10508 5-(1,2-dithiolan-3-yl)-N-[4-(1,2,3,4-tetrahydroacridin-9-ylamino)butyl]pentanamide::tacrine-lipoic acid hybrid 3

SMILES O=C(CCCCC1CCSS1)NCCCCNc1c2CCCCc2nc2ccccc12

InChI Key InChIKey=IEBFRRATFZBOGS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10508   

TargetCholinesterase(Homo sapiens (Human))
University Of Bologna

LigandPNGBDBM10508(5-(1,2-dithiolan-3-yl)-N-[4-(1,2,3,4-tetrahydroacr...)
Affinity DataIC50:  5.04nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcetylcholinesterase(Homo sapiens (Human))
University Of Bologna

LigandPNGBDBM10508(5-(1,2-dithiolan-3-yl)-N-[4-(1,2,3,4-tetrahydroacr...)
Affinity DataIC50:  35.2nMpH: 8.0 T: 2°CAssay Description:The cholinesterase assays were performed using colorimetric method reported by Ellman. Enzyme activity was determined by measuring the absorbance at...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed