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BDBM105837 US8575197, I-347

SMILES: CCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(cc1)-c1ccoc1

InChI Key: InChIKey=HOUBYRVMHAMDRQ-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 105837   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM105837
PNG
(US8575197, I-347)
Show SMILES CCOc1ccccc1C1C(C(=O)CC(C)C)C(=O)C(=O)N1c1ccc(cc1)-c1ccoc1
Show InChI InChI=1/C27H27NO5/c1-4-33-23-8-6-5-7-21(23)25-24(22(29)15-17(2)3)26(30)27(31)28(25)20-11-9-18(10-12-20)19-13-14-32-16-19/h5-14,16-17,24-25H,4,15H2,1-3H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 47n/an/an/an/an/an/a



Shionogi & Co., Ltd

US Patent


Assay Description
Inhibition assay using human P2X3 receptor gene (GeneBank accession number Y07683).


US Patent US8575197 (2013)


BindingDB Entry DOI: 10.7270/Q2CN72KP
More data for this
Ligand-Target Pair