BDBM8961 1,2,3,4-tetrahydro-9-acridinamine::1,2,3,4-tetrahydroacridin-9-amine::9-THA::9-amino-1,2,3,4-tetrahydroacridine (THA)::CHEMBL1337960::CHEMBL95::Cognex::Tacrine::Tracine::US8999994, Tacrine::cid_1935::tacrine.HCl

SMILES: c1ccc2c(c1)c(c3c(n2)CCCC3)N

InChI Key: InChIKey=YLJREFDVOIBQDA-UHFFFAOYSA-N

Data: 53 KI  774 IC50  5 Kd  3 EC50

PDB links: 7 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 845 hits for monomerid = 8961   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetylcholinesterase (Rat)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	223	n/a	n/a	n/a	n/a	8.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rat)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	92	n/a	n/a	n/a	n/a	8.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	250	n/a	n/a	n/a	n/a	8.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Bovine)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	8.0	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Horse)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Bovine)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	167	n/a	n/a	n/a	n/a	8.0	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	89	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Bovine)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	167	n/a	n/a	n/a	n/a	8.0	30
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	8.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rat)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	319	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rat)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	223	n/a	n/a	n/a	n/a	7.4	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rat)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	92	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Pacific electric ray)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rat)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	590	n/a	n/a	n/a	n/a	7.4	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rat)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Rat)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	223	n/a	n/a	n/a	n/a	7.4	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Rat)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	92	n/a	n/a	n/a	n/a	7.4	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Pacific electric ray)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.20	n/a	n/a	n/a	n/a	7.8	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	424	n/a	n/a	n/a	n/a	8.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	45.8	n/a	n/a	n/a	n/a	8.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	205	n/a	n/a	n/a	n/a	8.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	43.9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	190	n/a	n/a	n/a	n/a	8.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	47	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Pacific electric ray)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	157	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Bovine)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	446	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.03E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	147	n/a	n/a	n/a	n/a	7.2	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Cholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	36	n/a	n/a	n/a	n/a	7.2	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.46	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Horse)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0244	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Phosphoethanolamine N-methyltransferase 1 (Caenorhabditis elegans)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.34E+7	n/a	n/a	n/a	n/a	8.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Phosphoethanolamine N-methyltransferase 2 (Caenorhabditis elegans)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.50E+6	n/a	n/a	n/a	n/a	8.0	25
TBA									Citation and Details
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Mu-type opioid receptor (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	9.25E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
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5-hydroxytryptamine receptor 2A (Mouse)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	7.61E+4	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Human)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	56	n/a	n/a	n/a	n/a	8.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Horse)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.60	n/a	n/a	n/a	n/a	8.0	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Acetylcholinesterase (Electric eel)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	27	n/a	n/a	n/a	n/a	8.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Carboxylic ester hydrolase (Horse)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.20	n/a	n/a	n/a	n/a	8.0	n/a
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Amine oxidase [flavin-containing] A (Rat)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.03E+4	n/a	n/a	n/a	n/a	7.4	37
TBA									Citation and Details
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Amine oxidase [flavin-containing] B (Rat)	BDBM8961 (CHEMBL95 | Cognex | cid_1935 | CHEMBL1337960 | 1,2...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	7.4	37
TBA									Citation and Details
					More data for this Ligand-Target Pair