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BDBM106027 US8575197, I-537

SMILES: CC(C)C(=O)C1C(N(C(=O)C1=O)c1ccc(cc1)-c1ccc(C)o1)c1ccccc1CCC(=O)N(C)C

InChI Key: InChIKey=RSGUGMKSZPUJSI-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 106027   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM106027
PNG
(US8575197, I-537)
Show SMILES CC(C)C(=O)C1C(N(C(=O)C1=O)c1ccc(cc1)-c1ccc(C)o1)c1ccccc1CCC(=O)N(C)C
Show InChI InChI=1/C30H32N2O5/c1-18(2)28(34)26-27(23-9-7-6-8-20(23)13-17-25(33)31(4)5)32(30(36)29(26)35)22-14-11-21(12-15-22)24-16-10-19(3)37-24/h6-12,14-16,18,26-27H,13,17H2,1-5H3
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 83n/an/an/an/an/an/a



Shionogi & Co., Ltd

US Patent


Assay Description
Inhibition assay using human P2X3 receptor gene (GeneBank accession number Y07683).


US Patent US8575197 (2013)


BindingDB Entry DOI: 10.7270/Q2CN72KP
More data for this
Ligand-Target Pair