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BDBM106352 US8575197, II-265

SMILES: COc1ccccc1C1N(C(=O)c2n[nH]c(c12)C(C)(C)CO)c1ccc(cn1)-c1ccco1

InChI Key: InChIKey=RQTQJXFACSGKJS-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 106352   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
P2X purinoceptor 3


(Homo sapiens (Human))
BDBM106352
PNG
(US8575197, II-265)
Show SMILES COc1ccccc1C1N(C(=O)c2n[nH]c(c12)C(C)(C)CO)c1ccc(cn1)-c1ccco1
Show InChI InChI=1/C25H24N4O4/c1-25(2,14-30)23-20-21(27-28-23)24(31)29(22(20)16-7-4-5-8-18(16)32-3)19-11-10-15(13-26-19)17-9-6-12-33-17/h4-13,22,30H,14H2,1-3H3,(H,27,28)
PDB

KEGG

UniProtKB/SwissProt

GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 31n/an/an/an/an/an/a



Shionogi & Co., Ltd

US Patent


Assay Description
Inhibition assay using human P2X3 receptor gene (GeneBank accession number Y07683).


US Patent US8575197 (2013)


BindingDB Entry DOI: 10.7270/Q2CN72KP
More data for this
Ligand-Target Pair