BDBM106561 US8586600, III-6
SMILES CN(C)C\C=C\C(=O)Nc1ccc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc1C(F)(F)F
InChI Key InChIKey=WIVJEMFJDXIPRD-FNORWQNLSA-N
Data 5 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 106561
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Celgene Avilomics Research
US Patent
Celgene Avilomics Research
US Patent
Affinity DataIC50: 5.90nMAssay Description:Compounds may also be assayed as inhibitors of PDGFR in a manner substantially similar to the method described in Roberts, et al., Antiangiogen...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Celgene Avilomics Research
US Patent
Celgene Avilomics Research
US Patent
Affinity DataIC50: 3.99E+3nMAssay Description:Compounds may also be assayed as inhibitors of CKit in a manner substantially similar to the method described by Upstate (http://www.upstate.com/img/...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Celgene Avilomics Research
US Patent
Celgene Avilomics Research
US Patent
Affinity DataIC50: 8.10E+3nMAssay Description:Compounds may be screened for their ability to inhibit KDR using a standard coupled enzyme assay (Fox et al., Protein Sci., (1998) 7, 2249).More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Celgene Avilomics Research
US Patent
Celgene Avilomics Research
US Patent
Affinity DataIC50: 1.57E+3nMAssay Description:Compounds may also be assayed as inhibitors of CKit in a manner substantially similar to the method described by Upstate (http://www.upstate.com/img/...More data for this Ligand-Target Pair
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Celgene Avilomics Research
US Patent
Celgene Avilomics Research
US Patent
Affinity DataIC50: 216nMAssay Description:Compounds may also be assayed as inhibitors of CKit in a manner substantially similar to the method described by Upstate (http://www.upstate.com/img/...More data for this Ligand-Target Pair