BDBM106561 US8586600, III-6

SMILES CN(C)C\C=C\C(=O)Nc1ccc(NC(=O)c2ccc(C)c(Nc3nccc(n3)-c3cccnc3)c2)cc1C(F)(F)F

InChI Key InChIKey=WIVJEMFJDXIPRD-FNORWQNLSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 106561   

TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Celgene Avilomics Research

US Patent
LigandPNGBDBM106561(US8586600, III-6)
Affinity DataIC50:  5.90nMAssay Description:Compounds may also be assayed as inhibitors of PDGFR in a manner substantially similar to the method described in Roberts, et al., “Antiangiogen...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Celgene Avilomics Research

US Patent
LigandPNGBDBM106561(US8586600, III-6)
Affinity DataIC50:  3.99E+3nMAssay Description:Compounds may also be assayed as inhibitors of CKit in a manner substantially similar to the method described by Upstate (http://www.upstate.com/img/...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Celgene Avilomics Research

US Patent
LigandPNGBDBM106561(US8586600, III-6)
Affinity DataIC50:  8.10E+3nMAssay Description:Compounds may be screened for their ability to inhibit KDR using a standard coupled enzyme assay (Fox et al., Protein Sci., (1998) 7, 2249).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Celgene Avilomics Research

US Patent
LigandPNGBDBM106561(US8586600, III-6)
Affinity DataIC50:  1.57E+3nMAssay Description:Compounds may also be assayed as inhibitors of CKit in a manner substantially similar to the method described by Upstate (http://www.upstate.com/img/...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetMast/stem cell growth factor receptor Kit(Homo sapiens (Human))
Celgene Avilomics Research

US Patent
LigandPNGBDBM106561(US8586600, III-6)
Affinity DataIC50:  216nMAssay Description:Compounds may also be assayed as inhibitors of CKit in a manner substantially similar to the method described by Upstate (http://www.upstate.com/img/...More data for this Ligand-Target Pair
In DepthDetails US Patent