BDBM106743 CHEMBL1823373::US8586620, 161

SMILES CNCCCn1ccc2ccc(cc12)N=C(N)c1cccs1

InChI Key InChIKey=MKTCLWHCLZWKPK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 106743   

TargetNitric oxide synthase, brain(Homo sapiens (Human))
Neuraxon

US Patent
LigandPNGBDBM106743(CHEMBL1823373 | US8586620, 161)
Affinity DataIC50:  1.78E+3nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM106743(CHEMBL1823373 | US8586620, 161)
Affinity DataIC50:  1.18E+4nMAssay Description:Inhibition of recombinant human eNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine into [3H]-L-citrull...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Homo sapiens (Human))
Neuraxon

US Patent
LigandPNGBDBM106743(CHEMBL1823373 | US8586620, 161)
Affinity DataIC50:  1.78E+3nMAssay Description:Inhibition of recombinant human nNOS expressed in baculovirus infected insect Sf9 cells assessed as conversion of [3H]-L-arginine into [3H]-L-citrull...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Neuraxon

Curated by ChEMBL
LigandPNGBDBM106743(CHEMBL1823373 | US8586620, 161)
Affinity DataIC50:  9.91E+3nMAssay Description:Enzyme assay using recombinant human inducible NOS (iNOS), human endothelial constitutive NOS (eNOS) or human neuronal constitutive NOS (nNOS).More data for this Ligand-Target Pair
In DepthDetails US Patent