BDBM10678 US8846719, 291

SMILES Cc1onc(C2CCC(F)CN2)c1COc1ccc(cn1)C(=O)NC(C)(C)CO

InChI Key InChIKey=MIAIMIAKGNNYDJ-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 10678   

TargetGamma-aminobutyric acid receptor subunit alpha-5(Homo sapiens (Human))
Roche Palo Alto

US Patent
LigandPNGBDBM10678(US8846719, 291)
Affinity DataKi:  1.20nM ΔG°:  -11.3kcal/molepH: 7.5 T: 2°CAssay Description:Radioligand binding assays were carried out in a volume of 200 mL (96-well plates) which contained 100 mL of cell memebranes, [3H]flumazenil at a con...More data for this Ligand-Target Pair
In DepthDetails US Patent