BDBM106971 US8592457, 7-5

SMILES: COc1ccc(CNC(=O)c2cc(ncc2-c2nccs2)-c2cncc(C)c2)nc1OC

InChI Key: InChIKey=VSOUDUXMPUHJEU-UHFFFAOYSA-N

Data: 4 KI  5 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 106971   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Orexin/Hypocretin receptor type 1 (Human)	BDBM106971 (US8592457, 7-5) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Orexin receptor type 2 (Human)	BDBM106971 (US8592457, 7-5) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM106971 (US8592457, 7-5) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2C9 (Human)	BDBM106971 (US8592457, 7-5) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 2D6 (Human)	BDBM106971 (US8592457, 7-5) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM106971 (US8592457, 7-5) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a
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Orexin receptor type 2 (Human)	BDBM106971 (US8592457, 7-5) Show SMILES Show InChI	GoogleScholar	UniChem		0.950	-12.8	n/a	n/a	n/a	n/a	n/a	7.4	37
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Orexin receptor type 2 (Human)	BDBM106971 (US8592457, 7-5) Show SMILES Show InChI	GoogleScholar	UniChem		1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Orexin/Hypocretin receptor type 1 (Human)	BDBM106971 (US8592457, 7-5) Show SMILES Show InChI	GoogleScholar	UniChem		3.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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Cytochrome P450 3A4 (Human)	BDBM106971 (US8592457, 7-5) Show SMILES Show InChI	GoogleScholar	UniChem		1.94E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
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