BDBM107104 US8592371, 6::US9278976, (3S,5R)-5-[1-(cyclopropanesulfonyl)-1H,4H,5H,6H-pyrrolo[3,4-c]pyrazol-5-yl]-2-(2,5-difluorophenyl)oxan-3-amine

SMILES N[C@H]1C[C@H](COC1c1cc(F)ccc1F)N1Cc2cnn(c2C1)S(=O)(=O)C1CC1

InChI Key InChIKey=SUKBIIOMRBFEMR-XHNGYCAMSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107104   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM107104(US8592371, 6 | US9278976, (3S,5R)-5-[1-(cyclopropa...)
Affinity DataIC50:  1.60nMpH: 7.5 T: 2°CAssay Description:A continuous fluorometric assay is employed with the substrate Gly-Pro-AMC, which is cleaved by DPP-4 to release the fluorescent AMC leaving group. T...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM107104(US8592371, 6 | US9278976, (3S,5R)-5-[1-(cyclopropa...)
Affinity DataIC50:  1.60nMAssay Description:Enzyme assay using dipeptidyl peptidase-IV.More data for this Ligand-Target Pair
In DepthDetails US Patent