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BDBM107140 US8592415, 25

SMILES: CSCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1

InChI Key: InChIKey=UKJLMBLWPDZLHI-UHFFFAOYSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 107140   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase JAK3


(Homo sapiens (Human))
BDBM107140
PNG
(US8592415, 25)
Show SMILES CSCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1
Show InChI InChI=1S/C17H15N3OS/c1-22-11-17(21)19-13-6-4-5-12(9-13)16-10-18-14-7-2-3-8-15(14)20-16/h2-10H,11H2,1H3,(H,19,21)
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US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



Reaction Biology Corp

US Patent


Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2.


US Patent US8592415 (2013)


BindingDB Entry DOI: 10.7270/Q218354P
More data for this
Ligand-Target Pair
Non-receptor tyrosine-protein kinase TYK2


(Homo sapiens (Human))
BDBM107140
PNG
(US8592415, 25)
Show SMILES CSCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1
Show InChI InChI=1S/C17H15N3OS/c1-22-11-17(21)19-13-6-4-5-12(9-13)16-10-18-14-7-2-3-8-15(14)20-16/h2-10H,11H2,1H3,(H,19,21)
PDB

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UniProtKB/TrEMBL

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antibodypedia
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PC cid
PC sid
UniChem

Similars

US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



Reaction Biology Corp

US Patent


Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2.


US Patent US8592415 (2013)


BindingDB Entry DOI: 10.7270/Q218354P
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM107140
PNG
(US8592415, 25)
Show SMILES CSCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1
Show InChI InChI=1S/C17H15N3OS/c1-22-11-17(21)19-13-6-4-5-12(9-13)16-10-18-14-7-2-3-8-15(14)20-16/h2-10H,11H2,1H3,(H,19,21)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



Reaction Biology Corp

US Patent


Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2.


US Patent US8592415 (2013)


BindingDB Entry DOI: 10.7270/Q218354P
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK2


(Homo sapiens (Human))
BDBM107140
PNG
(US8592415, 25)
Show SMILES CSCC(=O)Nc1cccc(c1)-c1cnc2ccccc2n1
Show InChI InChI=1S/C17H15N3OS/c1-22-11-17(21)19-13-6-4-5-12(9-13)16-10-18-14-7-2-3-8-15(14)20-16/h2-10H,11H2,1H3,(H,19,21)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



Reaction Biology Corp

US Patent


Assay Description
In vitro kinase enzyme assay using Jak3, Jak2, Jak1, and Tyk2.


US Patent US8592415 (2013)


BindingDB Entry DOI: 10.7270/Q218354P
More data for this
Ligand-Target Pair