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BDBM107219 US8598345, Table 1-5

SMILES: Cn1ccc(NC(=O)c2cc(Oc3cccnc3)ccn2)n1

InChI Key: InChIKey=MNHWITHSQNVYKJ-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107219   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor


(Rattus norvegicus (Rat))
BDBM107219
PNG
(US8598345, Table 1-5)
Show SMILES Cn1ccc(NC(=O)c2cc(Oc3cccnc3)ccn2)n1
Show InChI InChI=1S/C15H13N5O2/c1-20-8-5-14(19-20)18-15(21)13-9-11(4-7-17-13)22-12-3-2-6-16-10-12/h2-10H,1H3,(H,18,19,21)
PDB
MMDB

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PC cid
PC sid
UniChem
US Patent
n/an/a 4.05E+3n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
mGluR5 activity was determined in a cell-based assay.


US Patent US8598345 (2013)


BindingDB Entry DOI: 10.7270/Q2RR1WX8
More data for this
Ligand-Target Pair