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BDBM107257 US8598345, Table 1-43

SMILES: CN(c1cncnc1)c1ccnc(c1)C(=O)Nc1ccccn1

InChI Key: InChIKey=OZAALONENRLXEY-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107257   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5


(Rattus norvegicus (Rat))
BDBM107257
PNG
(US8598345, Table 1-43)
Show SMILES CN(c1cncnc1)c1ccnc(c1)C(=O)Nc1ccccn1
Show InChI InChI=1S/C16H14N6O/c1-22(13-9-17-11-18-10-13)12-5-7-19-14(8-12)16(23)21-15-4-2-3-6-20-15/h2-11H,1H3,(H,20,21,23)
PDB
MMDB

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PC sid
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Similars

US Patent
n/an/a>1.00E+4n/an/an/an/an/an/a



Vanderbilt University

US Patent


Assay Description
mGluR5 activity was determined in a cell-based assay.


US Patent US8598345 (2013)


BindingDB Entry DOI: 10.7270/Q2RR1WX8
More data for this
Ligand-Target Pair