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BDBM107740 US8933095, 24

SMILES: CC(C)n1nc2N(O)C(=O)[C@@H](N)Cc2c1Cc1ccccc1

InChI Key: InChIKey=KTBFFEMTJRTXAE-ZDUSSCGKSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107740   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Kynurenine aminotransferase II (KAT II)


(Homo sapiens (Human))
BDBM107740
PNG
(US8933095, 24)
Show SMILES CC(C)n1nc2N(O)C(=O)[C@@H](N)Cc2c1Cc1ccccc1
Show InChI InChI=1S/C16H20N4O2/c1-10(2)19-14(8-11-6-4-3-5-7-11)12-9-13(17)16(21)20(22)15(12)18-19/h3-7,10,13,22H,8-9,17H2,1-2H3/t13-/m0/s1
PDB
MMDB

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PC cid
PC sid
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Similars

US Patent
n/an/a 63n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ...


Citation and Details
More data for this
Ligand-Target Pair
Kynurenine aminotransferase II (KAT II)


(Homo sapiens (Human))
BDBM107740
PNG
(US8933095, 24)
Show SMILES CC(C)n1nc2N(O)C(=O)[C@@H](N)Cc2c1Cc1ccccc1
Show InChI InChI=1S/C16H20N4O2/c1-10(2)19-14(8-11-6-4-3-5-7-11)12-9-13(17)16(21)20(22)15(12)18-19/h3-7,10,13,22H,8-9,17H2,1-2H3/t13-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 63n/an/an/an/an/an/a



Pfizer Inc.

US Patent


Assay Description
Formation of kynurenic acid (KYNA) is indirectly assessed by a decrease in light absorbance at 370 nm (OD370) as the L-kynurenine (KYN) substrate is ...


Citation and Details
More data for this
Ligand-Target Pair